Infectious Disease

Download e-book for iPad: An Appraisal of the Status of Chagas Disease in the United by Rodrigo Zeledon, Charles B. Beard, J.C. Pinto Dias, David A

By Rodrigo Zeledon, Charles B. Beard, J.C. Pinto Dias, David A Leiby, Patricia Dorn, Jose Rodrigues Coura

ISBN-10: 012397268X

ISBN-13: 9780123972682

This identify seriously reports outdated and new literature, aid to create larger information of the illness within the US and is helping within the review of definite epidemiological and public health and wellbeing issues.

During the 1st half the 20 th century, Chagas disorder was once assumed to be absent from the U.S. and regarded an unique disorder, until eventually the 1st indigenous instances have been stumbled on, virtually concurrently, in Texas, 1955. due to the fact that point 4 indigenous circumstances were documented in numerous areas within the state. even supposing the illness continues to be thought of unusual within the US, this disorder isn't longer an particular Latin American illness.

Physicians within the US are usually blind to the features of the illnesses, and are most probably overlooking in the neighborhood bought instances. The inflow of an predicted 300,000 Latin American immigrants with the Chagas parasite implies that there's an pressing desire for physicians and public future health officers to develop into aware.

  • Helps to create larger knowledge of Chagas sickness within the USA
  • Helps to judge epidemiological and public health and wellbeing issues
  • Facilitates actual and helpful destiny public health and wellbeing interventions

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Additional info for An Appraisal of the Status of Chagas Disease in the United States

Sample text

Protracta) into one eye. Parasites were observed in the blood as early as 14 days and up to 58 days after inoculation. The animals had fever, and three of them presented a typical bipalpebral edema in the eye even though the preauricular or cervical lymph nodes were not palpable. Postmortem histopathological studies revealed mild diffuse myocarditis with amastigotes in the heart muscle. Human strains from Panama and Venezuela produced the same clinical picture in some other infected monkeys. Diamond and Rubin (1956) inoculated six pigs, four lambs, and two goats, all 1 day old, with the Patuxent raccoon isolate of T.

A lymph node aspirate revealed amastigotes of T. , 2006). 44 Rodrigo Zeledón et al. In a retrospective study based on clinical histories from the Texas Veterinary Medical Diagnostic Laboratory, Meurs et al. (1998) studied the chronic stage of the disease and pointed out that the main clinical signs are exercise intolerance, lethargy, ascites, tachycardia, and inappetence. ECG abnormalities were detected in 10 of 11 dogs, consisting of arrhythmias and conduction disturbances, and the most common was RBBB, paralleling that reported in humans with chronic Chagas disease.

Yabsley and Noblet (2002b) characterized by biological and molecular methods (isoenzyme analysis, RAPD-PCR, and amplification of the nontranscribed region of the mini-exon gene) a low virulent strain from a raccoon, comparing it with a Brazilian virulent strain. The raccoon strain behaved as T. cruzi group II (Lineage 1). The authors were also able to detect DNA of T. cruzi in mice tissues by PCR. Roelling et al. S. isolates of T. cruzi from different origins (captive wildlife, domestic animals, triatomines, and humans) and concluded that only two genotypes were involved in these various hosts.

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An Appraisal of the Status of Chagas Disease in the United States by Rodrigo Zeledon, Charles B. Beard, J.C. Pinto Dias, David A Leiby, Patricia Dorn, Jose Rodrigues Coura


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